An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells

The serine/threonine kinase AKT is a central node in cell signaling. While aberrant AKT activation underlies the development of a variety of human diseases, how different patterns of AKT-dependent phosphorylation dictate downstream signaling and phenotypic outcomes remains largely enigmatic. Herein,...

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Detalles Bibliográficos
Autores principales: Zhou, Wenping, Li, Wenxue, Wang, Shisheng, Salovska, Barbora, Hu, Zhenyi, Tao, Bo, Di, Yi, Punyamurtula, Ujwal, Turk, Benjamin E., Sessa, William C., Liu, Yansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293293/
https://www.ncbi.nlm.nih.gov/pubmed/37365174
http://dx.doi.org/10.1038/s41467-023-39514-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293293/
https://www.ncbi.nlm.nih.gov/pubmed/37365174
http://dx.doi.org/10.1038/s41467-023-39514-1

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