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An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells
The serine/threonine kinase AKT is a central node in cell signaling. While aberrant AKT activation underlies the development of a variety of human diseases, how different patterns of AKT-dependent phosphorylation dictate downstream signaling and phenotypic outcomes remains largely enigmatic. Herein,...
Autores principales: | Zhou, Wenping, Li, Wenxue, Wang, Shisheng, Salovska, Barbora, Hu, Zhenyi, Tao, Bo, Di, Yi, Punyamurtula, Ujwal, Turk, Benjamin E., Sessa, William C., Liu, Yansheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293293/ https://www.ncbi.nlm.nih.gov/pubmed/37365174 http://dx.doi.org/10.1038/s41467-023-39514-1 |
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