Trimer stability of Helicobacter pylori HtrA is regulated by a natural mutation in the protease domain

The human pathogen Helicobacter pylori is a major risk factor for gastric disease development. Serine protease HtrA is an important bacterial virulence factor that cleaves the cell junction proteins occludin, claudin-8 and E-cadherin, which causes gastric tissue damage. Using casein zymography, we d...

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Detalles Bibliográficos
Autores principales: Zarzecka, Urszula, Tegtmeyer, Nicole, Sticht, Heinrich, Backert, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293373/
https://www.ncbi.nlm.nih.gov/pubmed/37183214
http://dx.doi.org/10.1007/s00430-023-00766-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293373/
https://www.ncbi.nlm.nih.gov/pubmed/37183214
http://dx.doi.org/10.1007/s00430-023-00766-9

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