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Trimer stability of Helicobacter pylori HtrA is regulated by a natural mutation in the protease domain
The human pathogen Helicobacter pylori is a major risk factor for gastric disease development. Serine protease HtrA is an important bacterial virulence factor that cleaves the cell junction proteins occludin, claudin-8 and E-cadherin, which causes gastric tissue damage. Using casein zymography, we d...
Autores principales: | Zarzecka, Urszula, Tegtmeyer, Nicole, Sticht, Heinrich, Backert, Steffen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293373/ https://www.ncbi.nlm.nih.gov/pubmed/37183214 http://dx.doi.org/10.1007/s00430-023-00766-9 |
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