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Microglia Signaling Pathway Reporters Unveiled Manganese Activation of the Interferon/STAT1 Pathway and Its Mitigation by Flavonoids

Neuroinflammatory responses to neurotoxic manganese (Mn) in CNS have been associated with the Mn-induced Parkinson-like syndromes. However, the framework of molecular mechanisms contributing to manganism is still unclear. Using an in vitro neuroinflammation model based on the insulated signaling pat...

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Detalles Bibliográficos
Autores principales: Mossine, Valeri V., Waters, James K., Sun, Grace Y., Gu, Zezong, Mawhinney, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293393/
https://www.ncbi.nlm.nih.gov/pubmed/37140843
http://dx.doi.org/10.1007/s12035-023-03369-w