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Impact of microRNA polymorphisms on high-dose methotrexate-related hematological toxicities in pediatric acute lymphoblastic leukemia

OBJECTIVES: It is well known that transporter and enzyme genes could be regulated by microRNA (miRNA) at the post-transcriptional level, and single-nucleotide polymorphisms (SNPs) in miRNA, which are involved in the miRNA production and structure, may impact the miRNA expression level and then influ...

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Detalles Bibliográficos
Autores principales: Zhan, Min, Liu, Ting, Zhang, Zhou, Wang, Guoqiang, Cao, Zhongqiang, Li, Xuejuan, Zeng, Hongwu, Mai, Huirong, Chen, Zebin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293614/
https://www.ncbi.nlm.nih.gov/pubmed/37384310
http://dx.doi.org/10.3389/fped.2023.1153767