Cargando…

Propofol inhibits neuroinflammation and metabolic reprogramming in microglia in vitro and in vivo

Microglial activation-induced neuroinflammation is closely related to the development of sepsis-associated encephalopathy. Accumulating evidence suggests that changes in the metabolic profile of microglia is crucial for their response to inflammation. Propofol is widely used for sedation in mechanic...

Descripción completa

Detalles Bibliográficos
Autores principales: Guan, Shuyuan, Sun, Lingbin, Wang, Xihua, Huang, Xirui, Luo, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293632/
https://www.ncbi.nlm.nih.gov/pubmed/37383725
http://dx.doi.org/10.3389/fphar.2023.1161810