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Theoretical and experimental studies on the interaction of biphenyl ligands with human and murine PD-L1: Up-to-date clues for drug design

Today it is widely recognized that the PD-1/PD-L1 axis plays a fundamental role in escaping the immune system in cancers, so that anti-PD-1/PD-L1 antibodies have been evaluated for their antitumor properties in more than 1000 clinical trials. As a result, some of them have entered the market revolut...

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Detalles Bibliográficos
Autores principales: Donati, Greta, D’Amore, Vincenzo Maria, Russomanno, Pasquale, Cerofolini, Linda, Amato, Jussara, Marzano, Simona, Salobehaj, Maria, Rizzo, Domenico, Assoni, Giulia, Carotenuto, Alfonso, La Pietra, Valeria, Arosio, Daniela, Seneci, Pierfausto, Fragai, Marco, Brancaccio, Diego, Di Leva, Francesco Saverio, Marinelli, Luciana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293680/
https://www.ncbi.nlm.nih.gov/pubmed/37384351
http://dx.doi.org/10.1016/j.csbj.2023.06.006