Dock2 generates characteristic spatiotemporal patterns of Rac activity to regulate neutrophil polarisation, migration and phagocytosis

INTRODUCTION: Rac-GTPases and their Rac-GEF activators play important roles in neutrophil-mediated host defence. These proteins control the adhesion molecules and cytoskeletal dynamics required for neutrophil recruitment to inflamed and infected organs, and the neutrophil effector responses that kil...

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Detalles Bibliográficos
Autores principales: Machin, Polly A., Johnsson, Anna-Karin E., Massey, Ellie J., Pantarelli, Chiara, Chetwynd, Stephen A., Chu, Julia Y., Okkenhaug, Hanneke, Segonds-Pichon, Anne, Walker, Simon, Malliri, Angeliki, Fukui, Yoshinori, Welch, Heidi C. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293741/
https://www.ncbi.nlm.nih.gov/pubmed/37383235
http://dx.doi.org/10.3389/fimmu.2023.1180886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293741/
https://www.ncbi.nlm.nih.gov/pubmed/37383235
http://dx.doi.org/10.3389/fimmu.2023.1180886

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