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Proline hydroxylase 2 (PHD2) promotes brown adipose thermogenesis by enhancing the hydroxylation of UCP1

OBJECTIVE: Brown adipose tissue (BAT) plays a crucial role in regulating non-shivering thermogenesis under cold exposure. Proline hydroxylases (PHDs) were found to be involved in adipocyte differentiation and lipid deposition. However, the effects of PHDs on regulatory mechanisms of BAT thermogenesi...

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Detalles Bibliográficos
Autores principales: Li, Fan, Zhang, Fenglin, Yi, Xin, Quan, Lu Lu, Yang, Xiaohua, Yin, Cong, Ma, Zewei, Wu, Ruifan, Zhao, Weijie, Ling, Mingfa, Lang, Limin, Hussein, Abdelaziz, Feng, Shengchun, Fu, Yiming, Wang, Junfeng, Liang, Shuyi, Zhu, Canjun, Wang, Lina, Zhu, Xiaotong, Gao, Ping, Xi, Qianyun, Zhang, Yongliang, Zhang, Lin, Shu, Gang, Jiang, Qingyan, Wang, Songbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293773/
https://www.ncbi.nlm.nih.gov/pubmed/37279828
http://dx.doi.org/10.1016/j.molmet.2023.101747