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The identification of high-performing antibodies for RNA-binding protein FUS for use in Western Blot, immunoprecipitation, and immunofluorescence

RNA-binding protein Fused-in Sarcoma (FUS) plays an essential role in various cellular processes. Mutations in the C-terminal domain region, where the nuclear localization signal (NLS) is located, causes the redistribution of FUS from the nucleus to the cytoplasm. In neurons, neurotoxic aggregates a...

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Detalles Bibliográficos
Autores principales: Alshalfie, Walaa, Fotouhi, Maryam, Ayoubi, Riham, You, Zhipeng, Southern, Kathleen, McPherson, Peter S., Laflamme, Carl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293799/
https://www.ncbi.nlm.nih.gov/pubmed/37384305
http://dx.doi.org/10.12688/f1000research.133220.2