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Multiple RNA- and DNA-binding proteins exhibit direct transfer of polynucleotides with implications for target-site search
We previously demonstrated that the polycomb repressive complex 2 chromatin–modifying enzyme can directly transfer between RNA and DNA without a free-enzyme intermediate state. Simulations suggested that such a direct transfer mechanism may be generally necessary for RNA to recruit proteins to chrom...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10293810/ https://www.ncbi.nlm.nih.gov/pubmed/37339225 http://dx.doi.org/10.1073/pnas.2220537120 |