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Prognostic impact of intra- and peritumoral immune cell subpopulations in head and neck squamous cell carcinomas – comprehensive analysis of the TCGA-HNSC cohort and immunohistochemical validation on 101 patients

BACKGROUND: Due to the expanding role of immune checkpoint inhibition in the treatment of head and neck squamous cell carcinoma, understanding immunological processes in the tumor microevironment (TME) has strong translational importance. Though analytical methods for a comprehensive analysis of the...

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Detalles Bibliográficos
Autores principales: Knebel, Moritz, Körner, Sandrina, Kühn, Jan Philipp, Wemmert, Silke, Brust, Lukas, Smola, Sigrun, Wagner, Mathias, Bohle, Rainer M., Morris, Luc G. T., Pandey, Abhinav, Schick, Bernhard, Linxweiler, Maximilian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294051/
https://www.ncbi.nlm.nih.gov/pubmed/37383237
http://dx.doi.org/10.3389/fimmu.2023.1172768