Ambient RNAs removal of cortex-specific snRNA-seq reveals Apoe(+) microglia/macrophage after deeper cerebral hypoperfusion in mice

BACKGROUND: Ambient RNAs contamination in single-nuclei RNA sequencing (snRNA-seq) is a challenging problem, but the consequences of ambient RNAs contamination of damaged and/or diseased tissues are poorly understood. Cognitive impairments and white/gray matter injuries are characteristic of deeper...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yuan, Tan, Jinyun, Yang, Kai, Fan, Weijian, Yu, Bo, Shi, Weihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294316/
https://www.ncbi.nlm.nih.gov/pubmed/37365617
http://dx.doi.org/10.1186/s12974-023-02831-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294316/
https://www.ncbi.nlm.nih.gov/pubmed/37365617
http://dx.doi.org/10.1186/s12974-023-02831-9

Ejemplares similares