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Non-POU Domain-Containing Octomer-Binding (NONO) protein expression and stability promotes the tumorigenicity and activation of Akt/MAPK/β-catenin pathways in human breast cancer cells

Breast cancer is one of the most common cancers with a high mortality rate, underscoring the need to identify new therapeutic targets. Here we report that non-POU domain-containing octamer-binding (NONO) protein is overexpressed in breast cancer and validated the interaction of the WW domain of PIN1...

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Detalles Bibliográficos
Autores principales: Lone, Bilal Ahmad, Siraj, Fouzia, Sharma, Ira, Verma, Shweta, Karna, Shibendra Kumar Lal, Ahmad, Faiz, Nagar, Preeti, Sachidanandan, Chetana, Pokharel, Yuba Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294335/
https://www.ncbi.nlm.nih.gov/pubmed/37370134
http://dx.doi.org/10.1186/s12964-023-01179-0