Cargando…

Amniotic fluid-derived exosomes attenuated fibrotic changes in POI rats through modulation of the TGF-β/Smads signaling pathway

In the current study, we investigated the regenerative effects of amniotic fluid exosomes (AF-Exos) in a rat model for premature ovarian insufficiency (POI). POI is a condition characterized by a decrease in ovarian function that can lead to infertility. We induced POI by administering cyclophospham...

Descripción completa

Detalles Bibliográficos
Autores principales: Nazdikbin Yamchi, Nahideh, Ahmadian, Shahin, Mobarak, Halimeh, Amjadi, Farhad, Beheshti, Rahim, Tamadon, Amin, Rahbarghazi, Reza, Mahdipour, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294370/
https://www.ncbi.nlm.nih.gov/pubmed/37370156
http://dx.doi.org/10.1186/s13048-023-01214-1