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Enpp1 deficiency caused chondrocyte apoptosis by inhibiting AMPK signaling pathway
OBJECTIVE AND BACKGROUND: The deficiency of ectonucleotide pyrophosphatase/phosphodiesterase 1 (Enpp1) causes the phenotype similar to knee osteoarthritis (OA). However, the molecular mechanism is poorly understood. METHOD: The global deletion of Enpp1 (Enpp1(−/−)) mice was created to analyze the ro...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294376/ https://www.ncbi.nlm.nih.gov/pubmed/37370114 http://dx.doi.org/10.1186/s13018-023-03923-1 |