Cargando…

Macrophage PTEN controls STING-induced inflammation and necroptosis through NICD/NRF2 signaling in APAP-induced liver injury

BACKGROUND: Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling has been known to play a critical role in maintaining cellular and tissue homeostasis, which also has an essential role in the inflammatory response. However, it remains unidentified whether and how the macrophage P...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Tao, Qu, Xiaoye, Zhao, Jiaying, Wang, Xiao, Wang, Qian, Dai, Jingjing, Zhu, Chuanlong, Li, Jun, Jiang, Longfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294406/
https://www.ncbi.nlm.nih.gov/pubmed/37370115
http://dx.doi.org/10.1186/s12964-023-01175-4