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Macrophage PTEN controls STING-induced inflammation and necroptosis through NICD/NRF2 signaling in APAP-induced liver injury

BACKGROUND: Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) signaling has been known to play a critical role in maintaining cellular and tissue homeostasis, which also has an essential role in the inflammatory response. However, it remains unidentified whether and how the macrophage P...

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Detalles Bibliográficos
Autores principales: Yang, Tao, Qu, Xiaoye, Zhao, Jiaying, Wang, Xiao, Wang, Qian, Dai, Jingjing, Zhu, Chuanlong, Li, Jun, Jiang, Longfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294406/
https://www.ncbi.nlm.nih.gov/pubmed/37370115
http://dx.doi.org/10.1186/s12964-023-01175-4

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