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Associations between DNA methylation and gene regulation depend on chromatin accessibility during transgenerational plasticity

BACKGROUND: Epigenetic processes are proposed to be a mechanism regulating gene expression during phenotypic plasticity. However, environmentally induced changes in DNA methylation exhibit little-to-no association with differential gene expression in metazoans at a transcriptome-wide level. It remai...

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Detalles Bibliográficos
Autores principales: Bogan, Samuel N., Strader, Marie E., Hofmann, Gretchen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294446/
https://www.ncbi.nlm.nih.gov/pubmed/37365578
http://dx.doi.org/10.1186/s12915-023-01645-8