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Resistance to aztreonam-avibactam due to a mutation of SHV-12 in Enterobacter

Aztreonam-avibactam is an important option against Enterobacterales producing metallo-β-lactamases (MBLs). We obtained an aztreonam-avibactam-resistant mutant of an MBL-producing Enterobacter mori strain by induced mutagenesis. Genome sequencing revealed an Arg244Gly (Ambler position) substitution o...

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Detalles Bibliográficos
Autores principales: Wu, Shikai, Ma, Ke, Feng, Yu, Zong, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294450/
https://www.ncbi.nlm.nih.gov/pubmed/37365592
http://dx.doi.org/10.1186/s12941-023-00605-y