Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice

BACKGROUND: Cholesterol gallstone disease is a common disease. Reducing cholesterol burden is important to prevent/treat gallstone. In this study, we investigated the application of diosgenin (DG) to prevent the formation of gallstone in mice. METHODS: Adult male C57BL/6J mice were fed with the lith...

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Detalles Bibliográficos
Autores principales: Shen, Weiyi, Shao, Wentao, Wang, Qihan, Wang, Bo, Zhao, Gang, Gu, Aihua, Jiang, Zhaoyan, Hu, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294472/
https://www.ncbi.nlm.nih.gov/pubmed/37370162
http://dx.doi.org/10.1186/s12929-023-00933-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294472/
https://www.ncbi.nlm.nih.gov/pubmed/37370162
http://dx.doi.org/10.1186/s12929-023-00933-3

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