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Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice

BACKGROUND: Cholesterol gallstone disease is a common disease. Reducing cholesterol burden is important to prevent/treat gallstone. In this study, we investigated the application of diosgenin (DG) to prevent the formation of gallstone in mice. METHODS: Adult male C57BL/6J mice were fed with the lith...

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Detalles Bibliográficos
Autores principales:	Shen, Weiyi, Shao, Wentao, Wang, Qihan, Wang, Bo, Zhao, Gang, Gu, Aihua, Jiang, Zhaoyan, Hu, Hai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294472/ https://www.ncbi.nlm.nih.gov/pubmed/37370162 http://dx.doi.org/10.1186/s12929-023-00933-3

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