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Mutated CYP17A1 promotes atherosclerosis and early-onset coronary artery disease
BACKGROUND: Coronary artery disease (CAD) is a multi-factor complex trait and is heritable, especially in early-onset families. However, the genetic factors affecting the susceptibility of early-onset CAD are not fully characterized. METHODS: In the present study, we identified a rare nonsense varia...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294473/ https://www.ncbi.nlm.nih.gov/pubmed/37370070 http://dx.doi.org/10.1186/s12964-023-01061-z |