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Mutated CYP17A1 promotes atherosclerosis and early-onset coronary artery disease

BACKGROUND: Coronary artery disease (CAD) is a multi-factor complex trait and is heritable, especially in early-onset families. However, the genetic factors affecting the susceptibility of early-onset CAD are not fully characterized. METHODS: In the present study, we identified a rare nonsense varia...

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Detalles Bibliográficos
Autores principales:	Wu, Ting-Ting, Zheng, Ying-Ying, Ma, Xiang, Xiu, Wen-Juan, Yang, Hai-Tao, Hou, Xian-Geng, Yang, Yi, Chen, You, Ma, Yi-Tong, Xie, Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294473/ https://www.ncbi.nlm.nih.gov/pubmed/37370070 http://dx.doi.org/10.1186/s12964-023-01061-z

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