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Interpretation of active-control randomised trials: the case for a new analytical perspective involving averted events
Active-control trials, where an experimental treatment is compared with an established treatment, are performed when the inclusion of a placebo control group is deemed to be unethical. For time-to-event outcomes, the primary estimand is usually the rate ratio, or the closely-related hazard ratio, co...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294491/ https://www.ncbi.nlm.nih.gov/pubmed/37365584 http://dx.doi.org/10.1186/s12874-023-01970-0 |