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Promoter hypermethylation and comprehensive regulation of ncRNA lead to the down-regulation of ZNF880, providing a new insight for the therapeutics and research of colorectal cancer

The human genome encodes more than 350 kinds of Krüppel-associated box (KRAB) domain-containing zinc-finger proteins (KZFPs), KRAB-type ZNF transcription factor family (KZNF) plays a vital role in gene regulatory networks. The KZNF family members include a large number of highly homologous genes, ge...

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Detalles Bibliográficos
Autores principales: Dong, Xiangqian, Zhang, Yinghui, Sun, Yang, Nan, Qiong, Li, Maojuan, Ma, Lanqing, Zhang, Lei, Luo, Juan, Qi, Yating, Miao, Yinglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294494/
https://www.ncbi.nlm.nih.gov/pubmed/37370088
http://dx.doi.org/10.1186/s12920-023-01571-2