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Mycobacterium tuberculosis-Specific CD4 T Cells Expressing Transcription Factors T-Bet or RORγT Associate with Bacterial Control in Granulomas

Despite the extensive research on CD4 T cells within the context of Mycobacterium tuberculosis (Mtb) infections, few studies have focused on identifying and investigating the profile of Mtb-specific T cells within lung granulomas. To facilitate the identification of Mtb-specific CD4 T cells, we iden...

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Detalles Bibliográficos
Autores principales: Grant, Nicole L., Kelly, Kristen, Maiello, Pauline, Abbott, Helena, O’Connor, Shelby, Lin, Philana Ling, Scanga, Charles A., Flynn, JoAnne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294621/
https://www.ncbi.nlm.nih.gov/pubmed/37039646
http://dx.doi.org/10.1128/mbio.00477-23