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CsrA-Mediated Translational Activation of the hmsE mRNA Enhances HmsD-Dependent C-di-GMP-Enabled Biofilm Production in Yersinia pestis

The plague bacterium, Yersinia pestis, forms a biofilm-mediated blockage in the flea foregut that enhances its transmission by fleabite. Biofilm formation is positively controlled by cyclic di-GMP (c-di-GMP), which is synthesized by the diguanylate cyclases (DGC), HmsD and HmsT. While HmsD primarily...

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Detalles Bibliográficos
Autores principales: Silva-Rohwer, Amelia R., Held, Kiara, Yakhnin, Helen, Babitzke, Paul, Vadyvaloo, Viveka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294631/
https://www.ncbi.nlm.nih.gov/pubmed/37191545
http://dx.doi.org/10.1128/jb.00105-23