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Generation and Functional Analysis of Defective Viral Genomes during SARS-CoV-2 Infection

Defective viral genomes (DVGs) have been identified in many RNA viruses as a major factor influencing antiviral immune response and viral pathogenesis. However, the generation and function of DVGs in SARS-CoV-2 infection are less known. In this study, we elucidated DVG generation in SARS-CoV-2 and i...

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Detalles Bibliográficos
Autores principales: Zhou, Terry, Gilliam, Nora J., Li, Sizhen, Spandau, Simone, Osborn, Raven M., Connor, Sarah, Anderson, Christopher S., Mariani, Thomas J., Thakar, Juilee, Dewhurst, Stephen, Mathews, David H., Huang, Liang, Sun, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294654/
https://www.ncbi.nlm.nih.gov/pubmed/37074178
http://dx.doi.org/10.1128/mbio.00250-23