Small Molecule Attenuates Bacterial Virulence by Targeting Conserved Response Regulator

Antibiotic tolerance within a biofilm community presents a serious public health challenge. Here, we report the identification of a 2-aminoimidazole derivative that inhibits biofilm formation by two pathogenic Gram-positive bacteria, Streptococcus mutans and Staphylococcus aureus. In S. mutans, the...

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Detalles Bibliográficos
Autores principales: Liu, Chang, Zhang, Hua, Peng, Xian, Blackledge, Meghan S., Furlani, Robert E., Li, Haoting, Su, Zhaoming, Melander, Roberta J., Melander, Christian, Michalek, Suzanne, Wu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294662/
https://www.ncbi.nlm.nih.gov/pubmed/37074183
http://dx.doi.org/10.1128/mbio.00137-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294662/
https://www.ncbi.nlm.nih.gov/pubmed/37074183
http://dx.doi.org/10.1128/mbio.00137-23

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