A Highly Substituted Ring-Fused 2-Pyridone Compound Targeting PrfA and the Efflux Regulator BrtA in Listeria monocytogenes

Listeria monocytogenes is a facultative Gram-positive bacterium that causes listeriosis, a severe foodborne disease. We previously discovered that ring-fused 2-pyridone compounds can decrease virulence factor expression in Listeria by binding and inactivating the PrfA virulence activator. In this st...

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Detalles Bibliográficos
Autores principales: Tükenmez, Hasan, Singh, Pardeep, Sarkar, Souvik, Çakır, Melike, Oliveira, Ana H., Lindgren, Cecilia, Vaitkevicius, Karolis, Bonde, Mari, Sauer-Eriksson, A. Elisabeth, Almqvist, Fredrik, Johansson, Jörgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294697/
https://www.ncbi.nlm.nih.gov/pubmed/37120759
http://dx.doi.org/10.1128/mbio.00449-23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294697/
https://www.ncbi.nlm.nih.gov/pubmed/37120759
http://dx.doi.org/10.1128/mbio.00449-23

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