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Immunogenicity and tolerability of a bivalent virus-like particle norovirus vaccine candidate in children from 6 months up to 4 years of age: A phase 2 randomized, double-blind trial

We conducted a dose-finding phase 2 study of the HilleVax bivalent virus-like particle (VLP) vaccine candidate (HIL-214) in two cohorts of children, 6–≤12 months and 1–≤4 years of age (N = 120 per cohort), in Panama and Colombia (ClinicalTrials.gov, identifier NCT02153112). On Day 1, children random...

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Detalles Bibliográficos
Autores principales: López, Pio, López-Medina, Eduardo, Sáez-Llorens, Xavier, deAntonio, Rodrigo, Masuda, Taisei, Mendelman, Paul M., Sherwood, James, Baehner, Frank, Borkowski, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294743/
https://www.ncbi.nlm.nih.gov/pubmed/37140558
http://dx.doi.org/10.1080/21645515.2023.2204787