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A method for the efficient evaluation of substrate-based cholinesterase imaging probes for Alzheimer’s disease

Cholinesterase (ChE) enzymes have been identified as diagnostic markers for Alzheimer disease (AD). Substrate-based probes have been synthesised to detect ChEs but they have not detected changes in ChE distribution associated with AD pathology. Probes are typically screened using spectrophotometric...

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Detalles Bibliográficos
Autores principales: Darvesh, Sultan, Banfield, Scott, Dufour, Maeve, Forrestall, Katrina L., Maillet, Hillary, Reid, G. Andrew, Sands, Dane, Pottie, Ian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294744/
http://dx.doi.org/10.1080/14756366.2023.2225797