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Understanding the structure–property relationship of bispecific monoclonal antibodies with Fc site-specific substitutions

Development of novel bispecific antibody (bsAb) platforms offers unprecedented opportunities for a wide variety of therapeutic applications. However, the expression and manufacturing of bsAbs with desired structures can be challenging. Owing to the uniqueness of each bsAb platform, more comprehensiv...

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Detalles Bibliográficos
Autores principales: Zhao, Bo, Zhao, Yunlong, Adaniya, Stephanie, Fu, Yue, Moon, Youmi, Heftel, Justin, Chen, Shuzhen, Xiao, Hui, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294755/
https://www.ncbi.nlm.nih.gov/pubmed/37357447
http://dx.doi.org/10.1080/19420862.2023.2228006