Cargando…

Sialylation: A Cloak for Tumors to Trick the Immune System in the Microenvironment

SIMPLE SUMMARY: Tumor cells accumulate sialylation in tissues via the coordination of sialyltransferases and sialidases. Tumor sialylation can block receptor and ligand binding at a physical level and actively inhibit immune activation by binding to the Siglec receptor of immune cells, creating an i...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Xiaoman, Chi, Kaijun, Zhang, Chairui, Liu, Quan, Yang, Ganglong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294807/
https://www.ncbi.nlm.nih.gov/pubmed/37372117
http://dx.doi.org/10.3390/biology12060832