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Sialylation: A Cloak for Tumors to Trick the Immune System in the Microenvironment
SIMPLE SUMMARY: Tumor cells accumulate sialylation in tissues via the coordination of sialyltransferases and sialidases. Tumor sialylation can block receptor and ligand binding at a physical level and actively inhibit immune activation by binding to the Siglec receptor of immune cells, creating an i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294807/ https://www.ncbi.nlm.nih.gov/pubmed/37372117 http://dx.doi.org/10.3390/biology12060832 |