DAPTA, a C-C Chemokine Receptor 5 (CCR5), Leads to the Downregulation of Notch/NF-κB Signaling and Proinflammatory Mediators in CD40(+) Cells in Experimental Autoimmune Encephalomyelitis Model in SJL/J Mice

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system characterized by motor deficits, cognitive impairment, fatigue, pain, and sensory and visual dysfunction. CD40, highly expressed in B cells, plays a significant role in MS pathogenesis. The experimental autoi...

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Detalles Bibliográficos
Autores principales: Alghibiwi, Hanan, Ansari, Mushtaq A., Nadeem, Ahmed, Algonaiah, Majed Ali, Attia, Sabry M., Bakheet, Saleh A., Albekairi, Thamer H., Almudimeegh, Sultan, Alhamed, Abdullah S., Shahid, Mudassar, Alwetaid, Mohammad Y., Alassmrry, Yasseen A., Ahmad, Sheikh F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294823/
https://www.ncbi.nlm.nih.gov/pubmed/37371605
http://dx.doi.org/10.3390/biomedicines11061511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294823/
https://www.ncbi.nlm.nih.gov/pubmed/37371605
http://dx.doi.org/10.3390/biomedicines11061511

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