Cargando…

DAPTA, a C-C Chemokine Receptor 5 (CCR5), Leads to the Downregulation of Notch/NF-κB Signaling and Proinflammatory Mediators in CD40(+) Cells in Experimental Autoimmune Encephalomyelitis Model in SJL/J Mice

Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system characterized by motor deficits, cognitive impairment, fatigue, pain, and sensory and visual dysfunction. CD40, highly expressed in B cells, plays a significant role in MS pathogenesis. The experimental autoi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alghibiwi, Hanan, Ansari, Mushtaq A., Nadeem, Ahmed, Algonaiah, Majed Ali, Attia, Sabry M., Bakheet, Saleh A., Albekairi, Thamer H., Almudimeegh, Sultan, Alhamed, Abdullah S., Shahid, Mudassar, Alwetaid, Mohammad Y., Alassmrry, Yasseen A., Ahmad, Sheikh F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294823/ https://www.ncbi.nlm.nih.gov/pubmed/37371605 http://dx.doi.org/10.3390/biomedicines11061511

Ejemplares similares

Aflatoxin B1 Exacerbates Genomic Instability and Apoptosis in the BTBR Autism Mouse Model via Dysregulating DNA Repair Pathway
por: Alshamrani, Ali A., et al.
Publicado: (2023)

The Exposure to Lead (Pb) Exacerbates Immunological Abnormalities in BTBR T(+) Itpr(3tf)/J Mice through the Regulation of Signaling Pathways Relevant to T Cells
por: Assiri, Mohammed A., et al.
Publicado: (2023)

Rituximab exerts its anti-arthritic effects via inhibiting NF-κB/GM-CSF/iNOS signaling in B cells in a mouse model of collagen-induced arthritis
por: Ansari, Mushtaq A., et al.
Publicado: (2023)

5-Aminoisoquinolinone, a PARP-1 Inhibitor, Ameliorates Immune Abnormalities through Upregulation of Anti-Inflammatory and Downregulation of Inflammatory Parameters in T Cells of BTBR Mouse Model of Autism
por: Alhosaini, Khaled, et al.
Publicado: (2021)

Histamine H4 Receptor Antagonist Ameliorates the Progression of Experimental Autoimmune Encephalomyelitis via Regulation of T-Cell Imbalance
por: Aldossari, Abdullah A., et al.
Publicado: (2023)

Chemokine Receptor 5 Antagonism Causes Reduction in Joint Inflammation in a Collagen-Induced Arthritis Mouse Model
por: Ansari, Mushtaq A., et al.
Publicado: (2021)

Upregulation of Inflammatory Mediators in Peripheral Blood CD40(+) Cells in Children with Autism Spectrum Disorder
por: Aldossari, Abdullah A., et al.
Publicado: (2023)

Aflatoxin B(1) Exposure Aggravates Neurobehavioral Deficits and Immune Dysfunctions of Th1, Th9, Th17, Th22, and T Regulatory Cell-Related Transcription Factor Signaling in the BTBR T(+)Itpr3(tf)/J Mouse Model of Autism
por: Alwetaid, Mohammad Y., et al.
Publicado: (2023)

Pharmacological Inhibition of STAT3 by Stattic Ameliorates Clinical Symptoms and Reduces Autoinflammation in Myeloid, Lymphoid, and Neuronal Tissue Compartments in Relapsing–Remitting Model of Experimental Autoimmune Encephalomyelitis in SJL/J Mice
por: Alhazzani, Khalid, et al.
Publicado: (2021)

Sinapic acid alleviates 5-fluorouracil-induced nephrotoxicity in rats via Nrf2/HO-1 signalling
por: Ahmad Ansari, Mushtaq, et al.
Publicado: (2023)

Dapagliflozin Mitigated Elevated Disomic and Diploid Sperm in a Mouse Model of Diabetes and Recover the Disrupted Ogg1, Parp1, and P53 Gene Expression
por: Albekairi, Norah A., et al.
Publicado: (2023)

Cadmium Exposure Is Associated with Behavioral Deficits and Neuroimmune Dysfunction in BTBR T(+) Itpr3tf/J Mice
por: Alanazi, Mohammed M., et al.
Publicado: (2023)

Impacts of the DPP-4 Inhibitor Saxagliptin and SGLT-2 Inhibitor Dapagliflozin on the Gonads of Diabetic Mice
por: Alshamrani, Ali A., et al.
Publicado: (2023)

The effect of omeprazole on the development of experimental autoimmune encephalomyelitis in C57BL/6J and SJL/J mice
por: Sands, Scott A, et al.
Publicado: (2014)

Autoimmune Cholangitis in the SJL/J Mouse is Antigen Non-specific
por: Sasaki, Motoko, et al.
Publicado: (2002)

Suppression of IgE antibody production in SJL mice. III. Characterization of a suppressor substance extracted from normal SJL spleen cells
Publicado: (1977)

Evaluation of Chromosomal Instability in Diabetic Rats Treated with Naringin
por: A. Bakheet, Saleh, et al.
Publicado: (2011)

Blockade of store-operated calcium entry sensitizes breast cancer cells to cisplatin therapy via modulating inflammatory response
por: Alhamed, Abdullah S., et al.
Publicado: (2023)

Properties of reticulum cell sarcomas in SJL/J mice. V. Nature of reticulum cell sarcoma surface antigen which induces proliferation of normal SJL/J T cells
Publicado: (1977)

Antimicrobial Potential of Pithecellobium dulce Seed Extract against Pathogenic Bacteria: In Silico and In Vitro Evaluation
por: Aldarhami, Abdu, et al.
Publicado: (2023)

DNA Hypomethylation Is Associated with Increased Inflammation in Peripheral Blood Neutrophils of Children with Autism Spectrum Disorder: Understanding the Role of Ubiquitous Pollutant Di(2-ethylhexyl) Phthalate
por: Alshamrani, Ali A., et al.
Publicado: (2023)

Thioredoxin 1 and Thioredoxin Reductase 1 Redox System Is Dysregulated in Neutrophils of Subjects with Autism: In Vitro Effects of Environmental Toxicant, Methylmercury
por: Alshehri, Samiyah, et al.
Publicado: (2023)

Histamine H4 Receptor Agonist, 4-Methylhistamine, Aggravates Disease Progression and Promotes Pro-Inflammatory Signaling in B Cells in an Experimental Autoimmune Encephalomyelitis Mouse Model
por: Alsaad, Abdulaziz M. S., et al.
Publicado: (2023)

Targeting Store-Operated Calcium Entry Regulates the Inflammation-Induced Proliferation and Migration of Breast Cancer Cells
por: Alqinyah, Mohammed, et al.
Publicado: (2023)

Proanthocyanidins Produce Significant Attenuation of Doxorubicin-Induced Mutagenicity via Suppression of Oxidative Stress
por: Attia, Sabry M., et al.
Publicado: (2010)

Inbred SJL mice recapitulate human resistance to Cryptococcus infection due to differential immune activation
por: Davis, M. J., et al.
Publicado: (2023)

Suppression of IgE antibody production in SJL mice. I. Nonspecific suppressor T cells
Publicado: (1976)

Calcineurin regulates the yeast synaptojanin Inp53/Sjl3 during membrane stress
por: Guiney, Evan L., et al.
Publicado: (2015)

Exposure to Methylmercury at Juvenile Stage Worsens Autism-Like Symptoms in Adult BTBR T+tf/J Mice Due to Lack of Nuclear Factor Erythroid 2-Related Factor 2 Signaling Upregulation in Periphery and Brain
por: Algahtani, Mohammad M., et al.
Publicado: (2023)

Loss of TRP53 (p53) accelerates tumorigenesis and changes the tumor spectrum of SJL/J mice
por: Branca, Jane A, et al.
Publicado: (2020)

ACTIVE SUPPRESSION OF IMMUNOGLOBULIN ALLOTYPE SYNTHESIS : I. CHRONIC SUPPRESSION AFTER PERINATAL EXPOSURE TO MATERNAL ANTIBODY TO PATERNAL ALLOTYPE IN (SJL x BALB/c)F(1) MICE
por: Jacobson, E. B., et al.
Publicado: (1972)

Correction: Utility of Dexrazoxane for the Attenuation of Epirubicin-Induced Genetic Alterations in Mouse Germ Cells
por: Attia, Sabry M., et al.
Publicado: (2016)

Utility of Dexrazoxane for the Attenuation of Epirubicin-Induced Genetic Alterations in Mouse Germ Cells
por: Attia, Sabry M., et al.
Publicado: (2016)

C4d at Crossroads Between Post-Infectious Glomerulonephritis and C3 Glomerulopathy
por: Bashir, Shaarif, et al.
Publicado: (2021)

(SWR x SJL)F1 mice: a new model of lupus-like disease
Publicado: (1994)

Suppression of IgE antibody production in SJL mice. IV. Interaction of primed and unprimed T cells
Publicado: (1979)

Littermate Influence on Infant Growth in Mice: Comparison of SJL/J and ICR as Cotransferred Carrier Embryos
por: Kaneko, Ryosuke, et al.
Publicado: (2014)

A common idiotype on SJL and C57BL/6 anti-(4-hydroxy-3-nitrophenyl) acetyl antibodies and its relationship with lambda chain production
Publicado: (1981)

Host genetic regulation of acute MHV-4 viral encephalomyelitis and acute experimental autoimmune encephalomyelitis in (BALB/cKe × SJL/J) recombinant-inbred mice()
por: Knobler, R.L., et al.
Publicado: (1985)

Carfilzomib Mitigates Lipopolysaccharide/D-Galactosamine/Dimethylsulfoxide-Induced Acute Liver Failure in Mice
por: Alhareth, Dhafer Y., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_6ov5p66b05k5ns6b3esd7mjiul