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Caffeine Inhibits Oxidative Stress- and Low Dose Endotoxemia-Induced Senescence—Role of Thioredoxin-1

The maintenance of Thioredoxin-1 (Trx-1) levels, and thus of cellular redox homeostasis, is vital for endothelial cells (ECs) to prevent senescence induction. One hallmark of EC functionality, their migratory capacity, which depends on intact mitochondria, is reduced in senescence. Caffeine improves...

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Detalles Bibliográficos
Autores principales: Merk, Dennis, Greulich, Jan, Vierkant, Annika, Cox, Fiona, Eckermann, Olaf, von Ameln, Florian, Dyballa-Rukes, Nadine, Altschmied, Joachim, Ale-Agha, Niloofar, Jakobs, Philipp, Haendeler, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294853/
https://www.ncbi.nlm.nih.gov/pubmed/37371974
http://dx.doi.org/10.3390/antiox12061244