A Comparative Genomic and Phylogenetic Investigation of the Xenobiotic Metabolism Enzymes of Cytochrome P450 in Elephants Shows Loss in CYP2E and CYP4A

SIMPLE SUMMARY: Our study investigates a specific genetic loss and duplication in elephants by comparing genomic data from 12 different mammalian species. We created a synteny map and phylogenetic tree of the selected species, which suggested that elephant CYP1–4 genes have undergone independent dup...

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Detalles Bibliográficos
Autores principales: Watanabe, Kanami, Kondo, Mitsuki, Ikenaka, Yoshinori, Nakayama, Shouta M. M., Ishizuka, Mayumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294912/
https://www.ncbi.nlm.nih.gov/pubmed/37370449
http://dx.doi.org/10.3390/ani13121939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294912/
https://www.ncbi.nlm.nih.gov/pubmed/37370449
http://dx.doi.org/10.3390/ani13121939

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