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Neuroprotective Efficacy of a Nanomicellar Complex of Carnosine and Lipoic Acid in a Rat Model of Rotenone-Induced Parkinson’s Disease

Oxidative stress, accompanied by mitochondrial dysfunction, is a key mechanism involved in the pathogenesis of Parkinson’s disease (PD). Both carnosine and lipoic acid are potent antioxidants, the applicability of which in therapy is hindered by their limited bioavailability. This study aimed to eva...

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Detalles Bibliográficos
Autores principales: Kulikova, Olga, Troshev, Dmitry, Berezhnoy, Daniil, Stvolinsky, Sergey, Timoshina, Yulia, Abaimov, Denis, Muzychuk, Olga, Latanov, Alexander, Fedorova, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294933/
https://www.ncbi.nlm.nih.gov/pubmed/37371945
http://dx.doi.org/10.3390/antiox12061215