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Role of NADPH Oxidase 4 in Corneal Endothelial Cells Is Mediated by Endoplasmic Reticulum Stress and Autophagy

Human corneal-endothelial cells (hCEnCs) are located on the inner layer of the cornea. Injury to CEnCs leads to permanent corneal edema, requiring corneal transplantation. NADPH oxidase 4 (NOX4) has been reported to be implicated in the pathogenesis of CEnCs diseases. Thus, we investigated the role...

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Detalles Bibliográficos
Autores principales: Ma, Dae Joong, Hwang, Jin Sun, Noh, Kyung Bo, Oh, Sun-Hee, Kim, Kyoung Wook, Shin, Young Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10294998/
https://www.ncbi.nlm.nih.gov/pubmed/37371958
http://dx.doi.org/10.3390/antiox12061228