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Efficacy of an Immunotherapy Combining Immunogenic Chimeric Protein Plus Adjuvant and Amphotericin B against Murine Visceral Leishmaniasis

SIMPLE SUMMARY: Visceral leishmaniasis is a tropical neglected disease caused by infection with Leishmania parasites. There are no human vaccines and the current drug treatments for infected patients are hampered by toxicity and the development of resistance. In our study, we have used an immunother...

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Detalles Bibliográficos
Autores principales: Vale, Danniele L., Freitas, Camila S., Martins, Vívian T., Moreira, Gabriel J. L., Machado, Amanda S., Ramos, Fernanda F., Pereira, Isabela A. G., Bandeira, Raquel S., de Jesus, Marcelo M., Tavares, Grasiele S. V., Ludolf, Fernanda, Chávez-Fumagalli, Miguel A., Galdino, Alexsandro S., Fujiwara, Ricardo T., Bueno, Lílian L., Roatt, Bruno M., Christodoulides, Myron, Coelho, Eduardo A. F., Lage, Daniela P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295016/
https://www.ncbi.nlm.nih.gov/pubmed/37372136
http://dx.doi.org/10.3390/biology12060851