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Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet

Carnosine and anserine supplementation markedLy reduce diabetic nephropathy in rodents. The mode of nephroprotective action of both dipeptides in diabetes, via local protection or improved systemic glucose homeostasis, is uncertain. Global carnosinase-1 knockout mice (Cndp1-KO) and wild-type litterm...

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Detalles Bibliográficos
Autores principales: Pfeffer, Tilman, Wetzel, Charlotte, Kirschner, Philip, Bartosova, Maria, Poth, Tanja, Schwab, Constantin, Poschet, Gernot, Zemva, Johanna, Bulkescher, Ruben, Damgov, Ivan, Thiel, Christian, Garbade, Sven F., Klingbeil, Kristina, Peters, Verena, Schmitt, Claus Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295340/
https://www.ncbi.nlm.nih.gov/pubmed/37372000
http://dx.doi.org/10.3390/antiox12061270