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Carnosinase-1 Knock-Out Reduces Kidney Fibrosis in Type-1 Diabetic Mice on High Fat Diet
Carnosine and anserine supplementation markedLy reduce diabetic nephropathy in rodents. The mode of nephroprotective action of both dipeptides in diabetes, via local protection or improved systemic glucose homeostasis, is uncertain. Global carnosinase-1 knockout mice (Cndp1-KO) and wild-type litterm...
Autores principales: | Pfeffer, Tilman, Wetzel, Charlotte, Kirschner, Philip, Bartosova, Maria, Poth, Tanja, Schwab, Constantin, Poschet, Gernot, Zemva, Johanna, Bulkescher, Ruben, Damgov, Ivan, Thiel, Christian, Garbade, Sven F., Klingbeil, Kristina, Peters, Verena, Schmitt, Claus Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295340/ https://www.ncbi.nlm.nih.gov/pubmed/37372000 http://dx.doi.org/10.3390/antiox12061270 |
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