The Beneficial Effect of Lomitapide on the Cardiovascular System in LDLr(−/−) Mice with Obesity

Objectives: Homozygous familial hypercholesteremia (HoFH) is a rare, life-threatening metabolic disease, mainly caused by a mutation in the LDL receptor. If untreated, HoFH causes premature death from acute coronary syndrome. Lomitapide is approved by the FDA as a therapy to lower lipid levels in ad...

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Detalles Bibliográficos
Autores principales: Munkhsaikhan, Undral, Kwon, Young In, Sahyoun, Amal M., Galán, María, Gonzalez, Alexis A., Ait-Aissa, Karima, Abidi, Ammaar H., Kassan, Adam, Kassan, Modar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295391/
https://www.ncbi.nlm.nih.gov/pubmed/37372017
http://dx.doi.org/10.3390/antiox12061287

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295391/
https://www.ncbi.nlm.nih.gov/pubmed/37372017
http://dx.doi.org/10.3390/antiox12061287

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