Tyrosine Nitroxidation Does Not Affect the Ability of α-Synuclein to Bind Anionic Micelles, but It Diminishes Its Ability to Bind and Assemble Synaptic-like Vesicles

Parkinson’s disease (PD) is characterized by dopaminergic neuron degeneration and the accumulation of neuronal inclusions known as Lewy bodies, which are formed by aggregated and post-translationally modified α-synuclein (αS). Oxidative modifications such as the formation of 3-nitrotyrosine (3-NT) o...

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Detalles Bibliográficos
Autores principales: Uceda, Ana Belén, Frau, Juan, Vilanova, Bartolomé, Adrover, Miquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295401/
https://www.ncbi.nlm.nih.gov/pubmed/37372040
http://dx.doi.org/10.3390/antiox12061310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295401/
https://www.ncbi.nlm.nih.gov/pubmed/37372040
http://dx.doi.org/10.3390/antiox12061310

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