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CCR4 Blockade Diminishes Intratumoral Macrophage Recruitment and Augments Survival of Syngeneic Pancreatic Cancer-Bearing Mice

Pancreatic cancer is known for its tumor microenvironment (TME), which is rich in stromal and immune cells supporting cancer growth and therapy resistance. In particular, tumor-associated macrophages (TAMs) are known for their angiogenesis- and metastasis-promoting properties, which lead to the fail...

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Detalles Bibliográficos
Autores principales: Khabipov, Aydar, Trung, Dung Nguyen, van der Linde, Julia, Miebach, Lea, Lenz, Maik, Erne, Felix, von Bernstorff, Wolfram, Schulze, Tobias, Kersting, Stephan, Bekeschus, Sander, Partecke, Lars Ivo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295441/
https://www.ncbi.nlm.nih.gov/pubmed/37371612
http://dx.doi.org/10.3390/biomedicines11061517