Megalin, cubilin, and Dab2 drive endocytic flux in kidney proximal tubule cells

The kidney proximal tubule (PT) elaborates a uniquely high-capacity apical endocytic pathway to retrieve albumin and other proteins that escape the glomerular filtration barrier. Megalin and cubilin/amnionless (CUBAM) receptors engage Dab2 in these cells to mediate clathrin-dependent uptake of filte...

Descripción completa

Detalles Bibliográficos
Autores principales: Rbaibi, Youssef, Long, Kimberly R., Shipman, Katherine E., Ren, Qidong, Baty, Catherine J., Kashlan, Ossama B., Weisz, Ora A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295476/
https://www.ncbi.nlm.nih.gov/pubmed/37126375
http://dx.doi.org/10.1091/mbc.E22-11-0510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10295476/
https://www.ncbi.nlm.nih.gov/pubmed/37126375
http://dx.doi.org/10.1091/mbc.E22-11-0510

Ejemplares similares